What marks the first stage in the development of biofilm?

The first stage in the development of biofilm is marked by the acquired pellicle on a clean tooth surface. This pellicle is a thin film composed mainly of glycoproteins derived from saliva that quickly forms over the enamel of the teeth after they have been cleaned.

The acquired pellicle serves as a welcoming surface for bacteria, providing them with a substrate to adhere to. This initial stage is crucial because it sets the stage for the subsequent attachment of oral bacteria, which leads to the formation of plaque and eventually tartar if not removed. Understanding this process is vital for dental professionals, as it emphasizes the importance of maintaining oral hygiene to prevent biofilm development and related dental issues.